Vincent Cryns

Lipid transfer proteins and PI4KIIα initiate nuclear p53-phosphoinositide signaling

Noah D Carrillo, Mo Chen, Poorwa Awasthi, Tianmu Wen, Xue Yang, Colin Sterling, Dhruv Brahmbhatt, Vincent L Cryns, Richard A Anderson

The Journal of biological chemistry. 2026 May 10. pmid:42107639, pmc:PMC13260207, doi:10.1016/j.jbc.2026.113123

Lipid transfer proteins and PI4KIIα generate a phosphoinositide-linked proteome

Noah D Carrillo, Mo Chen, Poorwa Awasthi, Tianmu Wen, Xiangqin Chen, Giang Vu, Dhruv Brahmbhatt, Michael Herlihy, Benjamin B Minkoff, Michael Sussman, Vincent L Cryns, Richard A Anderson

The Journal of biological chemistry. 2026 May 7. pmid:42097443, pmc:PMC13266111, doi:10.1016/j.jbc.2026.113089

NRF2 Stabilization by Isoform-Specific Nuclear Phosphoinositides in Stress Response

Yiting Tang, Yu Chen, Noah D Carrillo, Vincent L Cryns, Richard A Anderson, Jichao Sun, Mo Chen

Oral science and homeostatic medicine. 2026 March 30. pmid:41908074, pmc:PMC13021284, doi:10.26599/oshm.2026.9610041

Lipid Transfer Proteins and PI4KIIα Generate a Phosphoinositide-Linked Proteome

Noah D Carrillo, Mo Chen, Poorwa Awasthi, Tianmu Wen, Xiangqin Chen, Giang Vu, Dhruv Brahmbhatt, Michael Herlihy, Benjamin B Minkoff, Michael Sussman, Vincent L Cryns, Richard A Anderson

bioRxiv : the preprint server for biology. 2025 December 25. pmid:41446106, pmc:PMC12724503, doi:10.64898/2025.12.17.694959

The Role of Nuclear Phosphoinositides in the p53-MDM2 Nexus

Jeong Hyo Lee, Muhammad Khalil Salah, Xiangqin Chen, Nickolas Vladimir Kucherenko, Vincent L Cryns, Richard A Anderson

Cells. 2025 August 13. pmid:40801560, pmc:PMC12346208, doi:10.3390/cells14151126

Regulation of the MDM2-p53 nexus by a nuclear phosphoinositide and small heat shock protein complex

Jeong Hyo Lee, Mo Chen, Tianmu Wen, Richard A Anderson, Vincent L Cryns

The Journal of biological chemistry. 2025 July 28. pmid:40721017, pmc:PMC12409426, doi:10.1016/j.jbc.2025.110527

Agonist- and stress-driven compartmentalized phosphoinositide signaling in cells

Mo Chen, Jay Xiaojun Tan, Yue Sun, Narendra Thapa, Vincent L Cryns, Richard A Anderson

Biochimica et biophysica acta. Molecular and cell biology of lipids. 2025 July 6. pmid:40618839, doi:10.1016/j.bbalip.2025.159662

The poly(A) polymerase Star-PAP is regulated by stably associated phosphoinositide messengers

Tianmu Wen, Mo Chen, Vincent L Cryns, Richard A Anderson

The Journal of biological chemistry. 2025 June 26. pmid:40570960, pmc:PMC12284501, doi:10.1016/j.jbc.2025.110412

Regulation of NRF2 by stably associated phosphoinositides and small heat shock proteins in response to stress

Changliang Chen, Noah D Carrillo, Mo Chen, Tianmu Wen, Poorwa Awasthi, Richard A Anderson, Vincent L Cryns

The Journal of biological chemistry. 2025 June 14. pmid:40516875, pmc:PMC12273567, doi:10.1016/j.jbc.2025.110367

Regulation of the MDM2-p53 Nexus by a Nuclear Phosphoinositide and Small Heat Shock Protein Complex

Jeong Hyo Lee, Mo Chen, Tianmu Wen, Richard A Anderson, Vincent L Cryns

bioRxiv : the preprint server for biology. 2025 May 23. pmid:40406464, pmc:PMC12097681, doi:10.1101/2025.04.11.648454