Daniel Amador-Noguez

Decoupling of global metabolic flux and proteome partitioning in bacteria

Ryan Thiermann, Jin Yang, Aniket Zodage, Fukang She, Danny K Fung, Taylor Rytlewski, Farshad Abdollah-Nia, Fangzhou Xiao, John T Sauls, Sarah Cox, Zulfar Ghulam-Jelani, Victoria Castillo, Quinn A Paulsen, David M Stevenson, Daniel Amador-Noguez, James R Williamson, Jue D Wang, Suckjoon Jun

Science (New York, N.Y.). 2026 June 18. pmid:42313948, doi:10.1126/science.aeb6410

Kiss and spit metabolomics highlight the role of host purine metabolism during pathogen infection

Gina M Gallego-Lopez, William J Olson, Andres M Tibabuzo-Perdomo, David Stevenson, Daniel Amador-Noguez, Grant Lawrence, James W Leahy, Emmanuel Contreras Guzman, Melissa C Skala, Laura J Knoll

mSphere. 2026 June 15. pmid:42294622, doi:10.1128/msphere.00256-26

Understanding the role of pyruvate dehydrogenase in Listeria monocytogenes virulence

Matthew J Freeman, Noah J Eral, Abigail M Debrine, David M Stevenson, Daniel Amador-Noguez, John-Demian Sauer

Infection and immunity. 2026 May 29. pmid:42214391, doi:10.1128/iai.00505-25

Gut microbes mediate the synergistic effects of dietary cholesterol and saturated fat in driving fibrosing MASH

Jake B Hermanson, Samar A Tolba, Md Amran Gazi, Evan A Chrisler, Manpreet Kaur, Ashley M Sidebottom, Yongjun Liu, Guillermo Martinez-Boggio, Lauren N Lucas, Daniel Amador-Noguez, Federico E Rey, Vanessa A Leone

Gut microbes. 2026 May 11. pmid:42108649, pmc:PMC13166192, doi:10.1080/19490976.2026.2668121

Discovery of metabolites produced by reactions between central carbon metabolites and cysteine that mark inflammatory macrophages

Nicholas L Arp, Felicia Deng, Jorgo Lika, Gretchen L Seim, Paulo Falco Cobra, Carlos Mellado Fritz, Steven V John, Swetha Rathinaraj, Bridget E Shields, Daniel Amador-Noguez, Katherine Henzler-Wildman, Jing Fan

bioRxiv : the preprint server for biology. 2026 March 27. pmid:41889857, pmc:PMC13015485, doi:10.64898/2026.03.18.712640

Metabolic imbalance limits fermentation in microbes engineered for high-titer ethanol production

Bishal Dev Sharma, Eashant Thusoo, David M Stevenson, Daniel Amador-Noguez, Lee R Lynd, Daniel G Olson

mSystems. 2026 March 25. pmid:41879324, pmc:PMC13098246, doi:10.1128/msystems.00074-26

Genetic and metabolic drivers of membrane remodeling in Clostridium thermocellum under alcohol stress

Eashant Thusoo, Tyler Jacobson, Bishal D Sharma, Isabella M Colón, Lee R Lynd, Daniel G Olson, Daniel Amador-Noguez

mSystems. 2026 March 5. pmid:41784359, pmc:PMC13011478, doi:10.1128/msystems.01345-25

Investigation of bile salt hydrolase activity in human gut bacteria reveals production of conjugated secondary bile acids

Lauren N Lucas, Mallikarjun Jillella, Lea E Cattaneo, Bhavana Gangwar, Qijun Zhang, A P Clay, Robert L Kerby, David M Stevenson, Helen E Blackwell, Federico E Rey, Daniel Amador-Noguez

Nature communications. 2026 February 23. pmid:41730843, pmc:PMC13039732, doi:10.1038/s41467-026-68556-4

GPR41 deficiency alters the gut microbiota-bile acid axis, reduces ileal expression of Npc1l1, and attenuates hypercholesterolemia in male mice

Evan R Hutchison, Jillella Mallikarjun, Jung Ha Byun, Lauren N Lucas, Kazuyuki Kasahara, Michael Tallon, Qijun Zhang, Daniel Amador-Noguez, Yongjun Liu, Vanessa A Leone, Brian W Parks, Federico E Rey

Gut microbes. 2025 December 15. pmid:41395766, pmc:PMC12710913, doi:10.1080/19490976.2025.2598957

Physiological and metabolic responses of Zymomonas mobilis to lignocellulosic hydrolysate

Julio Rivera Vazquez, Edna Trujillo, Zach Wenger, Michael Botts, Joshua J Coon, Daniel Amador-Noguez

Microbiology spectrum. 2025 September 17. pmid:40960300, pmc:PMC12502597, doi:10.1128/spectrum.00610-25