Fan Xiao

PhD Student, Lamming Research Group

The role of protein restriction and BCAA restriction in metabolic health and Alzheimer’s disease.

Fan has a B.S. in Food Science from Huazhong Agricultural University and an M.S. in Nutrition from Zhejiang University. In her free time, she enjoys running and reading.

fxiao23@wisc.edu

Type: Graduate Students

Sleeve gastrectomy improves metabolic health, cognition, and Alzheimer’s Disease pathology in 3xTG mice

Reji Babygirija, Julia A Illiano, Michelle M Sonsalla, Grace Zhu, Twinkle Mathew, Tristan Molkentin, Meredith Peterson, Carolyn Winder, Fan Xiao, Justin M Wolter, Dudley W Lamming, David A Harris

bioRxiv : the preprint server for biology. 2026 May 4. pmid:42079275, pmc:PMC13131472, doi:10.64898/2026.04.21.719988
Female resistance to the metabolic benefits of protein restriction is reversed by ovariectomy in mice

Bailey A Knopf, Isaac Grunow, Brady Anderson, Tareq Rihawi, Michelle M Sonsalla, Mariah F Calubag, Reji Babygirija, Yang Liu, Fan Xiao, Chung-Yang Yeh, Dudley W Lamming

bioRxiv : the preprint server for biology. 2026 April 22. pmid:42017010, pmc:PMC13093968, doi:10.64898/2026.03.31.715667
Restriction of Individual Branched-Chain Amino Acids has Distinct Effects on the Development and Progression of Alzheimer’s Disease in 3xTg Mice

Reji Babygirija, Cara L Green, Michelle M Sonsalla, Izabelle Marie F Le, Fan Xiao, Sarah Yandell, Mariah F Calubag, Michaela E Trautman, Anna Tobon, Ryan Matoska, Chung-Yang Yeh, Charles I Opara, Isaac Grunow, Diana Vertein, Sophia Schlorf, Bailey A Knopf, Michael J Rigby, David A Harris, Mark P Keller, Alan D Attie, Luigi Puglielli, Cholsoon Jang, Dudley W Lamming

Advanced science (Weinheim, Baden-Wurttemberg, Germany). 2026 March 12. pmid:41817439, pmc:PMC13248761, doi:10.1002/advs.202515220
Ketogenesis is Dispensable for the Metabolic Adaptations to Caloric Restriction

Chung-Yang Yeh, Alexis L Borgelt, Brynn J Vogt, Alyssa A Clark, Ted T Wong, Isaac Grunow, Michelle M Sonsalla, Reji Babygirija, Yang Liu, Michaela E Trautman, Mariah F Calubag, Bailey A Knopf, Fan Xiao, Dudley W Lamming

Aging cell. 2025 December 10. pmid:41369866, pmc:PMC12741194, doi:10.1111/acel.70318
Restriction of individual branched-chain amino acids has distinct effects on the development and progression of Alzheimer’s disease in 3xTg mice

Reji Babygirija, Cara L Green, Michelle M Sonsalla, Fan Xiao, Mariah F Calubag, Michaela E Trautman, Anna Tobon, Ryan Matoska, Chung-Yang Yeh, Isaac Grunow, Diana Vertein, Sophia Schlorf, Bailey A Knopf, Michael J Rigby, Luigi Puglielli, Dudley W Lamming

bioRxiv : the preprint server for biology. 2025 August 8. pmid:40777466, pmc:PMC12330534, doi:10.1101/2025.07.24.663565
Tissue-Specific Effects of Dietary Protein on Cellular Senescence Are Mediated by Branched-Chain Amino Acids

Mariah F Calubag, Ismail Ademi, Isaac D Grunow, Lucia E Breuer, Reji Babygirija, Penelope Lialios, Sandra M Le, Michelle M Sonsalla, Julia A Illiano, Bailey A Knopf, Fan Xiao, Dennis Minton, Adam R Konopka, David A Harris, Dudley W Lamming

Aging cell. 2025 July 29. pmid:40726002, pmc:PMC12507398, doi:10.1111/acel.70176
Ketogenesis is dispensable for the metabolic adaptations to caloric restriction

Chung-Yang Yeh, Lexie Borgelt, Brynn J Vogt, Alyssa A Clark, Ted T Wong, Isaac Grunow, Michelle M Sonsalla, Reji Babygirija, Yang Liu, Michaela E Trautman, Mariah F Calubag, Bailey A Knopf, Fan Xiao, Dudley W Lamming

bioRxiv : the preprint server for biology. 2025 June 12. pmid:40501543, pmc:PMC12154805, doi:10.1101/2025.05.29.656153
Tissue-specific effects of dietary protein on cellular senescence are mediated by branched-chain amino acids

Mariah F Calubag, Ismail Ademi, Isaac Grunow, Lucia Breuer, Reji Babygirija, Penelope Lialios, Sandra Le, Dennis Minton, Michelle M Sonsalla, Julia Illiano, Bailey A Knopf, Fan Xiao, Adam R Konopka, David A Harris, Dudley W Lamming

bioRxiv : the preprint server for biology. 2025 January 27. pmid:39868338, pmc:PMC11761368, doi:10.1101/2025.01.13.632607